Cholesterol Levels May Link to Osteoporosis
A new study published in Clinical Immunology finds that there can be a potential link between high cholesterol and osteoporosis. According to recent reports, “Rita Effros, a professor of pathology at the David Geffen School of Medicine at UCLA, said she suspected the connection existed with the cell and tissue damage that came from exposure to fatty acids in cholesterol”.
The study focused on low-density lipoprotein (LDL) cholesterol, examining how high levels of oxidized LDL affected the bone and whether a T cell played a role in the process. Effros states, “both the resting and the activated T cells started churning out a chemical that stimulates cells whose sole purpose is to destroy bone”.
The next step will be exploring methods to control T cell response to oxidized LDL in an effort to develop immune-based approaches to prevent or slow bone loss, Effros says.
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